Red blood cell aggregation in nephrotic syndrome

Hemodynamic effects of red blood cell aggregation.

The influence of red blood cell (RBC) aggregation on blood flow in vivo has been under debate since early 1900's, yet a full understanding has still has not been reached. Enhanced RBC aggregation is well known to increase blood viscosity measured in rotational viscometers. However, it has been demonstrated that RBC aggregation may decrease flow resistance in cylindrical tubes, due to the format...

Rheology of red blood cell aggregation by computer simulation

The aggregation of red blood cells (RBC) induced by the interactions between RBCs is a dominant factor of the in vitro rheological properties of blood, and existing models of blood do not contain full cellular information. In this work, we introduce a new three-dimensional model that couples Navier–Stokes equations with cell interactions to investigate RBC aggregation and its effect on blood rh...

The Relationship between Blood Biomarkers Level and the Prognosis of Nephrotic Syndrome in the Children

Background Nephrotic syndrome (NS) characterized by a large amounts of protein into urine and a set of indications that include: protein in urine, low blood protein levels, high cholesterol levels, high triglyceride levels, and swelling. Therefore, aim of this study was to investigate the relationship between prognosis of nephrotic syndrome and blood biomarkers level in children of Arak city, I...

Influence of Graded Alterations of Red Blood Cell Aggregation on in Vivo Blood Flow Resistance

Effects of red blood cell aggregation on myocardial hematocrit gradient using two approaches to increase aggregation.

The normal transmyocardial tissue hematocrit distribution (i.e., subepicardial greater than subendocardial) is known to be affected by red blood cell (RBC) aggregation. Prior studies employing the use of infused large macromolecules to increase erythrocyte aggregation are complicated by both increased plasma viscosity and dilution of plasma. Using a new technique to specifically alter the aggre...